Contraindications for Steroid Use to treat COVID

Do steroids help fight COVID?

Both the World Health Organization and National Institutes of Health recommend against the use of steroids in non-critically ill patients with COVID-19.1,2  This recommendation is based largely on the Recovery Trial where of 1,535 patients with COVID-19 who did not require oxygen (non-critically ill) were randomized to steroids or usual care.3 The 28-day mortality rate was 17.8% (89/501) in the steroid group and 14.0% in the usual care group (145/1034). Effectively the 28-day mortality rate was 19% higher in the steroid group verses those receiving usual care.  Here is the source information for these studies:

1. Updated Jan. 14, 2022. Accessed Jan 31,2022.

2.–therapeutic-management/ Updated Jan 14, 2022. Accessed Jan 31, 2022.

3.        Lim W.S., Emberson J.R., Mafham M., et al. Dexamethasone in hospitalized patients with Covid-19. N. Engl. J. Med. 2021;384(8):693–704. doi: 10.1056/NEJMoa2021436.


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